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Newborn Gut Deficient Baby

Newborn Gut Deficiency is a Hidden Health Problem that Affects More than 90% of U.S. Infants

Research published in Scientific Reports reveals that the key beneficial bacteria, B. infantis, is missing in the vast majority of newborns.


Scientists assessed the current status of the gut microbiome in infants 0-6 months of age across the U.S.

Newborn Gut Deficiency

A nationwide metagenomic survey was performed and evaluated Newborn Gut Deficiency by measuring:

  • Abundance of beneficial and potentially pathogenic bacteria
  • Levels of antibiotic-resistant genes (ARGs)
  • Microbiome capacity to metabolize HMOs from breast milk

Findings revealed:

  • B. infantis is missing in more than 90% of newborns
  • The vast majority of infants have low functioning microbiomes
    • The infant gut microbiome is dominated by potentially pathogenic bacteria carrying high levels of ARGs
    • Almost all infants showed reduced capacity to metabolize human milk

Evivo (activated B. infantis EVC001) Solves Newborn Gut Deficiency

Scientists assessed the current status of the gut microbiome in infants 0-6 months of age across the U.S. 

Bacterial Family Chart

Most newborns do not acquire the beneficial bacteria B. infantis naturally, allowing potentially pathogenic bacteria to thrive and resulting in Newborn Gut Deficiency (NGD). Only Evivo is clinically proven to resolve NGD and provide functional, measurable benefits within days.

Feeding Evivo to babies is clinically shown to:

  • Colonize the infant gut with B. infantis EVC001 

  • Reduce potentially pathogenic bacteria in the infant gut by 80%

  • Reduce intestinal inflammation by 98%


Signs and Consequences of Newborn Gut Deficiency

Diaper rash, colic, and gas are signs of Newborn Gut Deficiency (NGD) in your infant patients. NGD is linked to intestinal inflammation which can disrupt immune development, impacting short- and long-term health. Long-term clinical consequences of gut dysbiosis can include allergies, atopic dermatitis, type 1 diabetes, and other autoimmune disorders.

Read the PublicationCasaburi et al. (2021) Scientific Reports

Metagenomic insights of the infant microbiome community structure and function across multiple sites in the United States

Key Takeaway

It is now estimated that more than 90% of infants in the US have Newborn Gut Deficiency, a dysbiotic gut microbe that fails to provide protection against pathogen colonization and maximize nutrition from HMOs. Feeding Evivo® (activated B. infantis EVC001) is a clinically proven way to promote a healthy microbiome in your infant patients.

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Newborn Gut Deficiency is Pervasive in U.S. Infants

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