The development of infant gut health and the immune system is a complex process. Exposure to beneficial bacteria, particularly B. infantis, is critical to infant gut health and immune system development. When B. infantis is introduced and colonized in the infant gut microbiome, it may protect the infant from developing proallergic responses: B. infantis does not antagonize dendritic cells, or antigen-presenting cells, and therefore helps develop an appropriate immune response.1
Evivo™ (activated B. infantis EVC001, ActiBif®) is a specific strain of B. infantis that is activated, meaning it is able to better utilize human breast milk components to grow and dominate the infant gut microbiome in a unique and superior manner. During our patented fermentation process, Evivo is grown on a substrate that activates the genes that allow it to consume the HMOs in breast milk better than any other gut bacteria. This gives Evivo an extra advantage in the baby’s gut.
Once B. infantis is established in an infant’s gut microbiome, it works to restore and protect the infant in a variety of ways. By outcompeting potential pathogens for growth, it can:
The activated B. infantis strain in Evivo works together with the special carbohydrates, or HMOs, in breast milk to restore the infant gut microbiome to its original, natural state. The unique and superior manner by which Evivo consumes HMOs allows it to protect the gut microbiome.
Feeding Evivo once daily with breast milk can help create a foundation for lifelong health—from the inside out.
1. Tannock GW. Commentary: remembrance of microbes past. Int J Epidemiol. 2005;34:13-15.
2. Bubnov RV, Spivak MY, Lazarenko LM et al. Probiotics and immunity: provisional role for personalized diets and disease prevention. EPMA J. 2015;6(1):14.
3. Fukuda S, Toh H, Hase K et al. Bifidobacteria can protect from enteropathogenic infection through production of acetate. Nature. 2011; 469(7331):543-547.
4. Ewaschuk JB, Diaz H, Meddings L et al. Secreted bioactive factors from Bifidobacterium infantis enhance epithelial cell barrier function. Am J Physiol Gastrointest Liver Physiol. 2008;295(5): G1025-G1034.
Get the latest updates.
More Media Coverage...
Human Milk Oligosaccharides (HMOs) are special carbohydrates that are food for baby’s gut bacteria. One key beneficial bacteria, B. infantis, is unique and able to capture all these carbohydrates that might otherwise be wasted, consuming them fully allowing B. infantis to grow and protect baby’s gut, and convert them into essential nutrients that are critical for baby’s developing metabolism and immune system.
Probiotics are ‘good’ bacteria that help keep your gut microbiome healthy. Historically, probiotics have been taken with the hope to relieve symptoms such as gas, bloating, or other digestive issues. However, new research has found that gut health is connected to other conditions such as colic, eczema, allergies, diabetes, and obesity and may have a much larger impact on overall health, beyond only symptomatic relief.
Prebiotics are carbohydrates that cannot be digested by the human body. Instead, they are ‘food’ for the gut microbiome. For babies, the most important prebiotics are found in breast milk and are called Human Milk Oligosaccharides (HMOs). HMOs are the third most abundant nutrient in breast milk and are critical to ‘feed’ good bacteria in baby’s gut.
A gut microbiome is a collection of trillions of microorganisms, or bacteria, that live in our intestines, or gut.
By nature’s design, beneficial and protective bacteria are passed from mom to baby during the birthing process, creating baby’s unique gut microbiome. However, the unintended consequences of modern medical practices such as antibiotics, c-sections, and formula feeding have led to a decrease in this mom to baby transfer.
In collaboration with the University of California Medical Center, we completed a clinical trial in which breast fed babies were given Evivo once a day for a month and were compared to breast fed babies who didn’t receive any probiotic. After a month, Evivo babies had significantly higher levels of the key good bacteria, B. infantis, in their gut compared to babies who didn’t receive any Evivo. This good bacteria is critical for proper immune system and metabolic development during the first six months of life.