Frequently Asked Questions

Evivo is safe to store at room temperature. You may notice that our packaging mentions placing Evivo in the freezer. But because each sachet is now specially designed to protect against temperature fluctuations, air, moisture, and light, Evivo can now be stored on the counter or in the pantry.

MFG is the Manufactured Date. Evivo is safe to feed 20 months past the Manufactured Date printed on the packaging.

Best if Used By Date is the recommended date when product should be used by to ensure that it is at its best quality, particularly as it relates to the number of live B. infantis EVC001 in the packet.

Evivo^® is a daily infant probiotic that contains B. infantis EVC001, a strain every baby needs. Clinically shown to work with breast milk, Evivo helps establish a healthy gut microbiome to support healthy digestive and immune function. Parents of babies who take Evivo report their babies have less gas and fussiness, improved sleep, improved stooling, and relief from diaper rash.

Evivo is clinically shown to be safe for babies, earned “best probiotic for families” by Mom’s Choice Award, and is Clean Label Project and Nutrasource IPRO™ (International Probiotic Standards) certified.

1. Strain – Not all probiotics are the same—bacterial strain matters.
2. Mechanism of action – the explainable process that describes how it works within the body.
3. Ability to thrive (colonization) – ability to thrive and establish an ongoing presence within the gut.

For babies receiving any amount of breast milk, probiotic strain B. infantis EVC001 is a strain that has been clinically shown to work with breast milk. Introducing B. infantis EVC001 during early infancy allows the gut microbiome to send signals that help support the immune system and may positively impact development.

Many probiotics claim, but Evivo actually explains how it works within baby.  

B. infantis EVC001, only in Evivo:  

1. Attaches to important nutrients in breast milk called human milk oligosaccharides (HMOs), to help healthy development 
2. Consumes these nutrients to thrive and protect within for digestive comfort  
3. Transforms nutrients to benefit healthy immune function 

Probiotics have been used in babies for many years and have been shown to be well tolerated. However, when choosing a probiotic, quality also matters. It is important to choose a probiotic that has been manufactured at the highest quality standards.

Most probiotics are bacterial strains that provide a health benefit to people. Probiotics should be named by their genus, species (subspecies when applicable), and a strain name. This information, especially the strain name, is crucial to conduct an evidence-based decision on a product.

Evivo works with breast milk to help your baby maximize the nutrients in the milk, resulting in less waste. That’s why changes in stool consistency are likely to occur, including a decrease in bowel movements. However, a change in bowel movements does not have to occur as every baby is unique and responds differently.

There’s a wide range of what’s considered normal with baby poop. Some babies have a bowel movement with every feeding, while others may have one per week. The color of an infant’s stool can also vary depending on factors like age and diet. In general, any shade of brown, yellow, orange, green are typical. When solid foods are introduced, stool color may change based on the new foods they are consuming. If stools are soft and the baby is producing enough wet diapers, eating well, and growing properly, don’t be concerned.

Research has identified hundreds of types of bacteria, and many are sold as probiotics for your baby, but many do not have an explainable process that describes how it works inside the body. That’s why Evivo is different.

With Evivo, baby can digest important breast milk nutrients called HMOs (Human Milk Oligosaccharides). While other probiotics pass through, the good bacteria (B. infantis EVC001) in Evivo captures and consumes HMOs to thrive and colonize within the gut. With up to 80% of our immune system in the gut, establishing a healthy gut microbiome is key to supporting immune function and positively impacting development.

Learn more about what matters when choosing a probiotic for baby, and how Evivo works.

Our current studies have been conducted feeding babies Evivo directly. We have no current data to support the ability to feed mom to pass on to baby.

Evivo is an infant probiotic and contains one powerful ingredient, B. infantis EVC001, which is finely milled and mixed with lactose, the main sugar found naturally in breast milk. When making Evivo, components used in the fermentation process contain soy and casein. If soy or milk is a concern, please consult your pediatrician before use.

Yes. Evivo may contain trace amounts of milk or dairy protein as a result of how it is processed. Evivo powder also contains lactose. We chose lactose as an ingredient because lactose is the main sugar that babies consume from breast milk. We use a high quality, a highly refined lactose focusing on keeping the product as pure as possible, but we cannot guarantee it is free of allergens, so we declare both soy and milk. Please consult your health care provider before use if you have concerns.

You can start feeding your baby Evivo immediately once they begin consuming breast milk.

Evivo works with breast milk to help establish a healthy gut microbiome and set your baby on a course to better health.

Research shows babies fed Evivo have:

• Significant improvement in breast milk digestion ^{1, 2}
• Reduced colic-associated symptoms ³
• Less gas and fussiness ³
• Significantly less diaper rash ³
• Better sleep within days ³
• Improved stooling ³

See evidence

1. Frese, Steven A., et al. “Persistence of supplemented Bifidobacterium longum subsp. infantis EVC001 in breastfed infants.” MSphere 2.6 (2017): e00501-17.​
2. Karav, Sercan, et al. “N-glycans from human milk glycoproteins are selectively released by an infant gut symbiont in vivo.” Journal of Functional Foods 61 (2019): 103485.​
3. Dimitratos, S. M., et al. “Symptomatic relief from at-home use of activated Bifidobacterium infantis EVC001 probiotic in infants: Results from a consumer survey on the effects on diaper rash, colic symptoms, and sleep.” Beneficial Microbes 12.4 (2021): 333-340.

We cannot guarantee Evivo to be free of common allergens. Specifically, Evivo contains B. infantis EVC001, which is finely milled and mixed with lactose, the main sugar found naturally in breast milk.

Given the way the product is processed, there may be trace amounts of residual milk and/or soy. While we do not expect any soy or milk to be present, per allergen regulations, we cannot guarantee a zero value and therefore declare both soy and milk.  If these allergens are a concern, please consult your pediatrician before use.

All babies, irrespective of delivery type, benefit from being fed Evivo. Even vaginally born babies may be missing beneficial bacteria in their gastrointestinal tract resulting in digestive discomfort.

Feeding baby Evivo with breast milk right after birth helps populate baby’s gut with B. infantis EVC001, a good bacteria strain clinically shown to work with breast milk to support digestive and immune health.

While our clinical research studies focus on babies, even toddlers who receive at least some breast milk may benefit from Evivo.

Evivo contains B. infantis EVC001, a good bacteria important for the infant gut microbiome right after birth. Breast milk and in particular HMOs help power B. infantis EVC001, so the longer the baby is receiving at least some breast milk the more baby may benefit. Evivo may be important in supporting the gut as infants transition away from breast milk and formula to complementary and solid foods.

Evivo can be mixed with breast milk, infant formula, or solids when feeding. Baby should have some amount of breast milk in their overall diet when feeding Evivo.

Evivo works with breast milk to help your baby maximize the nutrients in the milk, resulting in less waste. That’s why changes in stool consistency are likely to occur, including a decrease in bowel movements. However, a change in bowel movements does not have to occur as every baby is unique and responds differently.

There’s a wide range of what’s considered normal with baby poop. Some babies have a bowel movement with every feeding, while others may have one per week. The color of an infant’s stool can also vary depending on factors like age and diet. In general, any shade of brown, yellow, orange, green are typical. When solid foods are introduced, stool color may change based on the new foods they are consuming. If stools are soft and the baby is producing enough wet diapers, eating well, and growing properly, don’t be concerned.

Decades of research by our founders uncovered breast milk nourishes baby and a specific bacterium, B. infantis. When breast milk promotes the growth of B. infantis EVC001, the good bacteria in Evivo, it creates a protective environment in the gut. With up to 80% of our immune system in our gut, establishing a healthy gut microbiome helps benefit immune function and positively impacts development.

Hear about our story and learn more about the science behind Evivo.

Yes. We recommend mixing 1 sachet with a single feeding amount (formula or breast milk). If your baby doesn’t finish the bottle, discard the leftovers after 30 minutes.

For infants who can’t tolerate a 3 – 5 ml volume in one feeding, consider making the thin paste

If your baby spits up, it’s fine to wait until the next day to feed Evivo again. B. infantis EVC001, the good bacteria in Evivo can maintain a presence in baby’s gut from prior feedings. If baby continues to spit up, we recommend trying a different feeding method. As a guide, for consistency, we’ve provided suggested amounts of breast milk to mix with 1 sachet.

1) Directly from finger, nipple or pacifier – 5 to10 drops (for paste)
2) Poured directly into Bottle – Single feeding amount or 2 oz
3) Via spoon, oral syringe, or medicine dispenser pacifier – 1 tsp (approx. 5 mL)

For infants who can’t tolerate a 3 – 5 ml volume in one feeding, consider making the thin paste.

You can continue feeding Evivo as long as your baby is receiving some breast milk.

Breast milk contains important nutrients called Human Milk Oligosaccharides (HMOs) intended to feed a specific bacteria, B. infantis. Evivo contains B. infantis EVC001, the good gut bacteria that digest HMOs.

B. infantis EVC001 captures and consumes HMOs to thrive and colonize the gut to promote the colonization of good bacteria, then releases signaling molecules that help guide immune function.

Evivo can be fed any time of day that best fits your family’s lifestyle. It may help to give Evivo at the start of a feeding so baby is likely to swallow more of it.

The recommended serving is one sachet daily mixed with breast milk, formula, or solids.

It’s ok, just give baby 1 sachet for the next feeding. The good bacteria in Evivo can maintain a presence in baby’s gut from prior feedings.

Yes. You can continue using Evivo as long your baby is still consuming breast milk. It can help continue supporting your baby’s gut health during the transition to solids.

You can feed Evivo right after birth when your baby starts consuming breast milk. Introducing B. infantis EVC001, the single strain in Evivo, during early infancy establishes a healthy gut microbiome. With 80% of the immune system in the gut, early attention helps benefit immune function and positively impact development.

Yes. Evivo is for babies fed any amount of breast milk and can be mixed with formula, breast milk, or solids.

You can add Evivo to thawed or freshly pumped breast milk. When you warm up breast milk, add Evivo after heating.

Evivo can be added after warming the breast milk. Evivo should not be heated directly.

For your convenience, there are several ways to feed your baby Evivo. What’s most important is finding the method and consistency that works best for you and your baby.

Mix 1 sachet into breast milk, formula, or solids. Feed immediately. Discard leftovers. If mixing with breast milk or formula, we’ve provided suggested amounts to mix with 1 sachet to help with consistency.

1) Directly from finger, nipple or pacifier – 5 to 10 drops (for paste)
2) Pour directly into bottle – Single feeding amount or 2 oz
3) Spoon, oral syringe, or medicine dispenser pacifier – 1 tsp (approx. 5 mL)

Consider making the thin paste for infants who can’t tolerate a 3 – 5 ml volume in one feeding.

Evivo has a very mild taste. Once mixed, it takes on the flavor of the breast milk, formula, or solid. Adding more milk, formula, or solid may provide a milder taste. You may notice a mild scent when you open a sachet of Evivo. This is normal and due to the natural fermentation of the good bacteria in Evivo, B. infantis EVC001.

Babies take time to adapt to changes in their microbiomes, especially when introducing new products or transitioning from one probiotic to another. During this period, it is normal for their digestive systems to undergo changes — Evivo is filling their belly with good bacteria.

The adjustment period can take up to 2 weeks. Baby’s stool should be soft, but frequency may decrease, and the color can vary depending on age and diet. In general, any shade of brown, yellow, orange, or green are normal. If baby’s stool is hard or pebble-like, they may be constipated, and we would recommend parents contact their healthcare provider.

Evivo can be mixed with breast milk, infant formula, or solids when feeding. Baby should have some amount of breast milk in their overall diet when feeding Evivo.

We’re continually looking to improve how we serve you, and that includes our product’s packaging. If you receive a package from us that looks different than what you’ve received in the past, rest assured it contains the same trusted Evivo product.

Designed to meet the highest standards for safety and quality, we continue to take all necessary measures to ensure that the product inside the package protects against temperature fluctuations, air, moisture, and light. For added convenience and flexibility, on top of a new look, Evivo can now be stored at room temperature.

Clean Label products are a clear step toward truth in labeling, giving parents who care about food and product safety additional peace of mind when it comes to heavy metals, pesticide residues, plasticizers, and other concerning chemicals. Beyond protecting your baby, when you buy products with Clean Label Project certifications, you’re sending a message to food and consumer product manufacturers that environmental and public health matter.

In addition to routine lab testing and formulation review, Clean Label Project performs random sampling and testing to ensure ongoing compliance with standards.

Clean Label Project tests products utilizing elements of European baby food regulations to set maximum contaminant thresholds for food, supplements, and other consumer products targeting pregnant women, infants, lactating mothers, and children.

Clean Label Project tests products against standards set by the State of California Environmental Health Hazard Assessment Office’s Proposition 65 list—considered the strictest regulation in the U.S. for protecting consumers from industrial and environmental contaminants and chemicals of concern.

Clean Label Project is a national nonprofit committed to transparency in food and consumer product labeling. They award products that emphasize purity and surpass standard regulations.

Research has identified hundreds of types of bacteria, and many are sold as probiotics for your baby, but many do not have an explainable process that describes how it works inside the body. That’s why Evivo is different.

With Evivo, baby can digest important breast milk nutrients called HMOs (Human Milk Oligosaccharides). While other probiotics pass through, the good bacteria (B. infantis EVC001) in Evivo captures and consumes HMOs to thrive and colonize within the gut. With up to 80% of our immune system in the gut, establishing a healthy gut microbiome is key to supporting immune function and positively impacting development.

Learn more about what matters when choosing a probiotic for baby, and how Evivo works.

The manufacturing of Evivo involves a comprehensive testing program, where we use the latest technology to ensure every lot is free of potentially harmful contaminants. Each lot includes a Certificate of Analysis, demonstrating it meets rigorous testing standards. Evivo has strict specifications, and we only source high-quality ingredients from reputable vendors.

Evivo was awarded the Clean Label Project Certification. The Clean Label Project is a national nonprofit committed to transparency in food and consumer product labeling. They award and certify products that emphasize purity and surpass regulations.

Decades of research by our founders uncovered breast milk nourishes baby and a specific bacterium, B. infantis. When breast milk promotes the growth of B. infantis EVC001, the good bacteria in Evivo, it creates a protective environment in the gut. With up to 80% of our immune system in our gut, establishing a healthy gut microbiome helps benefit immune function and positively impacts development.

Hear about our story and learn more about the science behind Evivo.

Our current studies have been conducted feeding babies Evivo directly. We have no current data to support the ability to feed mom to pass on to baby.

Evivo works with breast milk to help establish a healthy gut microbiome and set your baby on a course to better health.

Research shows babies fed Evivo have:

• Significant improvement in breast milk digestion ^{1, 2}
• Reduced colic-associated symptoms ³
• Less gas and fussiness ³
• Significantly less diaper rash ³
• Better sleep within days ³
• Improved stooling ³

See evidence

1. Frese, Steven A., et al. “Persistence of supplemented Bifidobacterium longum subsp. infantis EVC001 in breastfed infants.” MSphere 2.6 (2017): e00501-17.​
2. Karav, Sercan, et al. “N-glycans from human milk glycoproteins are selectively released by an infant gut symbiont in vivo.” Journal of Functional Foods 61 (2019): 103485.​
3. Dimitratos, S. M., et al. “Symptomatic relief from at-home use of activated Bifidobacterium infantis EVC001 probiotic in infants: Results from a consumer survey on the effects on diaper rash, colic symptoms, and sleep.” Beneficial Microbes 12.4 (2021): 333-340.

We cannot guarantee Evivo to be free of common allergens. Specifically, Evivo contains B. infantis EVC001, which is finely milled and mixed with lactose, the main sugar found naturally in breast milk.

Given the way the product is processed, there may be trace amounts of residual milk and/or soy. While we do not expect any soy or milk to be present, per allergen regulations, we cannot guarantee a zero value and therefore declare both soy and milk.  If these allergens are a concern, please consult your pediatrician before use.

Yes. Evivo can be taken with other medicines and antibiotics. Consult your pediatrician to ensure Evivo is suitable for your baby.

All insurance plans are different. We recommend contacting your insurance provider directly. Download our Evivo Reimbursement Request Form, which your healthcare provider can complete and send to your insurance company to request reimbursement.

B. infantis is a select subspecies uniquely adapted to capture and consume Human Milk Oligosaccharides (HMOs) from breast milk. However, not all strains of B. infantis can consume HMOs to the same extent.

B. infantis EVC001, only in Evivo, contains the full complement of genes that can utilize the full breadth of HMOs most efficiently and effectively. See evidence here.

Evivo is available at Evivo.com, Amazon.com, local healthcare professional offices, and independent baby stores. Visit our store locator to find if there is location close to you for in store purchase.

Like any changes to the diet, it may take baby a few days to adjust. If you are ready to stop Evivo, you can stop immediately, and restart at any time. If stopping disrupts your baby’s routine, you can start reducing the amount per day and or move to every few days to minimize sudden changes to the diet.

The infant gut microbiome is dynamic, continuously undergoing changes and while Evivo binds to the human milk oligosaccharides (HMOs) and colonizes, other factors like food, environment, and medications such as antibiotics can also influence the microbiome. Therefore, Evivo can always be an option to help minimize GI discomfort.

Evivo can be used in combination with other probiotics. Research has identified hundreds of types of bacteria, and many are sold as probiotics for your baby. But not all products work the same. For babies, consider the following:

1) The bacteria strain listed in the ingredients
2) If it works with baby’s diet, and
3) Whether there is an explanation on how it works within the body

Probiotics are living organisms that need food to provide a health benefit. Evivo contains B. infantis EVC001, the strain clinically shown to digest breast milk HMOs (human milk oligosaccharides) to help establish a healthy gut microbiome and support immune health.

Learn about what matters when choosing a probiotic for baby and how Evivo works.

Pediatricians are great resources. Why gut health is important to baby is a great conversation to have with your pediatrician. You can also hear from doctors why they recommend Evivo here.

Evivo is less than $5.00 per day for as long as your baby is consuming breast milk. Only Evivo contains B. infantis EVC001, the bacterial strain shown to work with breast milk.

While our clinical research studies focus on babies, even toddlers who receive at least some breast milk may benefit from Evivo.

Evivo contains B. infantis EVC001, a good bacteria important for the infant gut microbiome right after birth. Breast milk and in particular HMOs help power B. infantis EVC001, so the longer the baby is receiving at least some breast milk the more baby may benefit. Evivo may be important in supporting the gut as infants transition away from breast milk and formula to complementary and solid foods.

All insurance plans are different. We recommend contacting your insurance provider directly. Download our Evivo Reimbursement Request Form, which your healthcare provider can complete and send to your insurance company to request reimbursement.

All shipments receive a FedEx tracking number, which you will receive via email from Evivo. If you have trouble tracking a package, or have an issue with delivery, please contact FedEx directly.

Signature is not required for orders placed on store.evivo.com

Evivo does not ship to addresses containing P.O. boxes.

Infinant Health Inc offers shipping within the continental United States, Puerto Rico, Canada, Hong Kong SAR, Philippines, and Singapore.

New Year’s Day, Memorial Day, Independence Day, Labor Day, Thanksgiving Day, Christmas Day

Before you place your order, please review your shopping basket carefully. Once you place an order, you can’t change or cancel it. Please read the FAQs to ensure Evivo is right for your baby before ordering.

Before sending merchandise back to Infinant Health, please submit a request to return merchandise purchased on store.evivo.com to our support team at customersupport@evivo.com. Our Return Policy explains when and how to return merchandise purchased on store.evivo.com.

We accept Visa, MasterCard, American Express, Discover, Amazon Payments, and PayPal Payments. We also offer flexible payment plans through Afterpay.

While our clinical research studies focus on babies, even toddlers who receive at least some breast milk may benefit from Evivo.

Evivo contains B. infantis EVC001, a good bacteria important for the infant gut microbiome right after birth. Breast milk and in particular HMOs help power B. infantis EVC001, so the longer the baby is receiving at least some breast milk the more baby may benefit. Evivo may be important in supporting the gut as infants transition away from breast milk and formula to complementary and solid foods.