Frequently Asked Questions
Browse below by category of our most common questions for Evivo products.
About Evivo (4)
Breast milk contains important nutrients called Human Milk Oligosaccharides (HMOs), which babies cannot digest on their own. Instead, HMOs are designed to nourish beneficial bacteria in the infant gut.
Evivo contains B. infantis EVC001, a clinically studied strain uniquely adapted to consume HMOs as its primary food source. By capturing and utilizing these nutrients, B. infantis EVC001 can thrive in the infant gut and help establish a healthy gut microbiome.
A healthy gut microbiome plays an important role in supporting digestive and immune health during early infancy.
Not all probiotics function the same way. Many probiotics pass through the digestive tract without a clearly understood mechanism for how they work in infants.
Evivo contains B. infantis EVC001, a clinically studied strain uniquely adapted to consume Human Milk Oligosaccharides (HMOs), important nutrients found in breast milk. While babies cannot digest HMOs themselves, B. infantis EVC001 captures and consumes these nutrients, allowing that good bacterium to thrive and become established in the infant gut.
As B. infantis EVC001 utilizes HMOs, it helps support the development of a healthy gut microbiome, which plays an important role in digestive and immune health.
Evivo is a daily infant probiotic containing the clinically studied strain of B. infantis EVC001, a beneficial bacterium specially adapted to work with breast milk. By consuming important nutrients in breast milk called Human Milk Oligosaccharides (HMOs), B. infantis EVC001 helps establish a healthy gut microbiome during early infancy.
A healthy gut microbiome plays an important role in supporting digestive and immune health. Parents of babies who use Evivo often report improvements in digestive comfort, including less gas and fussiness, improved stooling patterns, better sleep, and relief from diaper rash.
EVC001 B. infantis is unique from other B. infantis strains and has likely the largest published bodies of clinical and mechanistic evidence of any commercially available B. infantis strain and is only found in Evivo products.
Both products contain B. infantis EVC001, the clinically studied strain, only found in Evivo. The primary differences are the delivery format and the ingredients.
Evivo Powder is a single-ingredient product containing B. infantis EVC001 and meant to be mixed with a small amount of breast milk, formula, or expressed milk before administration.
Evivo Drops contain B. infantis EVC001 is suspended in olive oil and also provides Vitamin D3. The liquid format may be preferred by families looking for a convenient daily option that combines probiotic and vitamin D supplementation.
Families may choose the product that best fits their feeding routine and preferences.
Using Evivo (7)
Evivo is intended for infants and can be introduced as early as the first days of life. We recommend Evivo for babies 0-36 months to allow for the optimal seeding of the microbiome. If your baby was born prematurely or has a complex medical condition, consult your healthcare provider before use.
Yes. Evivo can be used with formula-fed infants. However, because B. infantis EVC001 naturally utilizes HMOs found in breast milk, we recommend using it with a formula containing HMOs or oligosaccharides, or supplementing with an HMO powder.
Most formulas include oligosaccharides or HMOs, look on the label for: “FOS”, “GOS”, “Oligosaccharide”, “HMOs” or specific HMOs like “2’FL, 6’SL, 3’SL, or LNT”.
- There are several ways to give Evivo to your baby. What’s most important is finding the method that works best for your family’s feeding routine.
Evivo Drops
- Shake the bottle before use.
- Dispense 6 drops onto a spoon, into a bottle of breast milk or formula, or mix with solids.
- Feed immediately and discard any leftovers.
Evivo Powder
- Mix 1 sachet with breast milk, formula, or solids.
- Feed immediately and discard any leftovers.
- Powder may also be mixed into a small volume of milk to create a paste for administration by finger, pacifier, spoon, or oral syringe. It can also be placed directly on the nipple.
For babies who are sensitive to larger feeding volumes, mixing the powder into a smaller amount of milk may help make administration easier.
Many families choose to continue Evivo during the transition to solid foods. If you have questions about your baby’s specific feeding journey, consult your pediatrician or healthcare provider.
Yes. The yellow substance in Evivo Drops is B. infantis EVC001, the beneficial bacterium contained in the product. Because the probiotic is suspended in olive oil, some settling is normal.
Before each use, shake the bottle vigorously. Then turn the bottle completely upside down and hold it still over a spoon. The drops may take a few moments to dispense. Avoid shaking the bottle while it is upside down, as this can make dispensing more difficult.
If you miss a serving, simply resume your normal schedule the next day. Do not give extra servings to make up for a missed dose. Evivo can be given any time of day.
Evivo Powder: The recommended serving is one packet per day.
Evivo Drops: The recommended serving is six drops per day.
Some babies may benefit from starting with a smaller amount and gradually increasing to the full serving. For example, families may choose to start with ½ packet of Evivo Powder or 2 drops of Evivo Drops daily for several days before working up to the full recommended serving.
What to Expect (3)
Many of the changes associated with Evivo occur inside the gut microbiome and may not always be visible. While some parents notice improvements in digestion, stooling patterns, gas, fussiness, sleep, or diaper rash, others may not observe obvious outward changes.
Because every baby’s microbiome is unique, individual experiences can vary. Even when visible changes are not apparent, B. infantis EVC001 is working with the HMOs in breast milk and formula to help establish a healthy gut microbiome.
In research studies conducting utilizing Evivo strain EVC001, it was found in 100% of the babies who were given it.
As your baby’s gut microbiome changes, you may notice changes in stool color, consistency, frequency, odor, or gas patterns. Some babies may also experience temporary digestive changes such as increased gas or fussiness as beneficial bacteria become established in the gut.
If your baby seems sensitive to the transition, consider starting with a smaller serving—such as ½ packet of Evivo Powder or 2 drops of Evivo Drops daily—and gradually increasing to the full recommended serving as tolerated.
If your baby becomes gassy, consider starting with a smaller serving—such as ½ packet of Evivo Powder or 2 drops of Evivo Drops daily—and gradually increasing to the full recommended serving as tolerated.
Ingredients and Safety (6)
During the manufacturing process, dairy and soy derived materials are used during fermentation. Only trace amounts are expected to remain in the finished product. While Evivo does not expect intact dairy or soy proteins, it cannot guarantee the complete absence of these materials.
Evivo’s packaging is specifically designed to help protect from normal temperature fluctuations that can occur during shipping and handling. Based on our stability testing, the product can withstand sustained temperatures of up to 100°F (38°C) for as long as one week before any meaningful loss of potency is expected to occur.
Short-term temperature fluctuations during transit are expected and have been accounted for in our packaging and stability studies, so brief exposure to warmer temperatures is generally not a cause for concern.
That said, for long-term storage and to ensure maximum potency throughout the product’s shelf life, we recommend storing Evivo at or below 70°F (21°C) whenever possible.
Evivo is safe to store at room temperature at 70°F (21°C) or below. Cold storage during shipping is not necessary.
Evivo Powder: Each sachet is designed to protect against temperature fluctuations, air, moisture, and light. Powder packets may be stored at room temperature in a pantry, cabinet, or on the counter and do not require refrigeration or freezer storage.
Evivo Drops: Store at room temperature away from direct light and moisture, at 70°F (21°C) or below. Refrigeration is not required. Do not freeze the bottle. Once opened, discard any remaining drops 6 weeks after opening.
The ingredients in Evivo vary slightly depending on the product format.
Evivo Powder contains B. infantis EVC001 and lactose, a naturally occurring sugar found in breast milk.
Evivo Drops contain B. infantis EVC001 suspended in olive oil and provide 400IU of Vitamin D3.
Both products contain the same clinically studied strain of B. infantis, EVC001, and are designed to support the development of a healthy infant gut microbiome.
Evivo Drops: Once opened, discard any remaining product 6 weeks after opening. As a general rule, unopened bottles typically have a shelf life of at least 12 months from the date of purchase when stored according to package instructions.
Evivo Powder: Unopened powder sachets typically have a shelf life of at least 12 months from the date of purchase when stored according to package instructions.
Evivo conducts routine quality and stability testing to help ensure product safety, potency, and quality throughout its shelf life. To maintain product quality, store Evivo in a cool, dry location and follow all storage instructions provided on the packaging.
Ordering (3)
Eligibility may vary depending on your specific HSA or FSA plan. Please consult your plan administrator for details regarding reimbursement eligibility.
Evivo is available through the official Evivo website, Amazon and select retail partners.
Please visit our Return Policy page for the most current information regarding refunds, exchanges, and eligibility requirements.